Clean FRCS notes with inline figures
Perthes disease
•Xray pelvis of skeletally immature patient with left hip pathology
•Left femoral proximal epiphysis appeared flattened and irregular, fragmented with lateral extrusion, cystic changes over metaphyseal area. The medial joint space is also widened. There is also lucency over lateral epiphysis, consistent with Gage sign.
•Contralateral hip not involved (10% bilateral, never same time)
•Working diagnosis would be Perthes disease. According to Waldenstrom classification, it looks to me the patient is in the fragmentation phase
*Waldenstrom classification
•Initial
•Fragmentation
•Reossification
•Remodeling
•Ddx are 1. septic arthritis, 2 Meyer’s disease 3. MED
•(bilateral Ddx: hypothyroid, lipid storage disease, meyers dysplasia, MED, sickle cell)
•Hx and PE would focus on
•Age, gender, body built
•Onset of symptoms
•Clinical at risk signs (FOOBS)
•R/O Ddx
•ROM (reduced abduction and IR, Trendelenburg gait, Catterall sign: hip flexion with obligatory external rotation)
Further investigations
•WBC (infection), lipid (storage disorder), ESR, CRP, bone profile (tumour), TSH (hypothyroid), peripheral smear (sickle cell)
XR: Frog leg lateral
•+/- USG, aspiration if suspecting infection
Aim of treatment
•Pain control (rest analgesics)
•Maintain ROM (physio, temporary NWB)
•Contain hip during critical period of “biologic plasticity”, during creeping substitution, so the femoral head remodels with less incongruity (limits deformity and loss of sphericity) *abduction and IR*
Natural history:
•Classic Iowa study with a 50yr FU that 40% need arthroplasty if left untreated. Counsel patient regarding containment. Still has a possibility of future OA
•Nonsurgical containment: in abduction and IR
Indication for surgical containment
For this case:
Lateral pillar classification Class B or B/C
•>8yo treat surgically for containment→ improve outcome according to Herring’s study
•Proximal femoral varus osteotomy
•Prerequisites include
•- Timing – fragmentation phase
•- Containable
•→ Sx – good range
•→ XR – spherical and congruent reduction, containable upon abduction XR / intraop arthrogram
Operative steps
•Good preop plan to estimate the amount of varus needed to obtain good containment
•GA
•Adductor release may be indicated if tight
Lateral subvastus approach
•Periosteum elevated
•Choose appropriate size of paediatric proximal locking plate (3.5mm if <35kg, 5mm if >35kg)
•Set guiding jig based on plate angle and desired amount of varus (jig angle (current neck shaft angle) = plate angle (smaller)+ desired amount of varus produced)
•Fix plate proximally then remove it
•Mark rotation before osteotomy
•Use 2 k wires, one above and one below the osteotomy for rotational correction
•Perform femoral osteotomy using an oscillating saw
•Fix plate proximally then distally
•Add some internal rotation or extension for better containment
•Postop
•NWB walking
•HKAFO
•FU till maturity
Outcome depends on Stulberg classification:
•I normal
•II spherical congruent
•III non spherical (mushroom), congruent
•IV non spherical (concave articular surface) congruent
•V non spherical (flat), incongruent
•Other problems: LLD, trendelenburg, pain (labral tear, loose body, hinged abduction, FAI)
the etiology:
•1. Anatomical
•2. Hydrostatic pressure
•3. Thrombophilic
What is the blood supply to the femoral head in 4-9yo patients?
•<4yo: equal contribution by MFCA and LFCA
•4-10yo: LFCA regress and supply metaphysis only
•10-14yo: ligamentum teres contribution further decrease
•>14yo: anastomosis between the three systems (epiphyseal, metaphyseal, ligamentum teres)
•*What are the at risk sign (FOOBS)
•Clinical and radiological
•Clinical
•Female
•Old
•Obese
•Bilateral
•Stiffness
Radiological (Caterall at risk signs)
•Gage sign (inverted v shape radiolucency lateral to epiphysis)
•Horizontal physis
•Lateral subluxation of femoral head
•Calcification lateral to epiphysis
•Metaphyseal cyst (later added)
Lateral Pillar Classification (based on AP Xray, compare both sides, by Herring, guide management and prognosis)
•Lateral pillar: 25%, lateral to lucent line
•Central pillar: 50%
•Medial pillar: 20-35%
•A = normal height
•B = >50%
•B/C = exactly 50% + depressed relative to central pillar, very narrow lateral pillar >50% of original height, very little ossification but > 50% original height
•C = <50%
Treatment
Nonoperative containment
•Observation, activity restriction, NWB and ROM exercise (abd +IR)
•Petri cast. A frame (need to wear if for 6 months to 1 year) (problem, cannot guarantee abduction)
Operative containment
•1. Proximal femoral VDRO (varus) (at most 20deg) or ROWO (rot open wedge osteot.). Problems: short limb and Trendelenburg gait
•2. Pelvic osteotomy (for old child >8, as proximal femur does not remodel as much)
•Containable: re-directional (Salter) [problem: potential lengthening leading to increase pressure on head leading to AVN]
•Combination with femoral osteotomy increase coverage by 20%
•Shelf to prevent lateral subluxation / no longer containable,
•Chiari
•Valgus osteotomy for hinged abduction (reposition hinge, correct shortening from fixed adduction, improve abductor function)
•*** Advantage of surgical containment is the patient will go through fragmentation phase faster according to B Joseph
Herring’s study
•Prospective multi center study of 450 affected hips with patients of age 6+
•2004 JBJS
Prognosis depends on age and Herring stage
•A and B <8 did well regardless of treatment
•B, B/C > 8 improve outcome with surgery
•B/C <8, C poor regardless of treatment
no difference in outcomes between nonop treatment
•no difference in outcomes between femoral or acetabular osteotomies
•no significant effect regardless of treatment in those <8yo
•Limitation: AP view, 7 month of symptoms before reliable classification, 1/3 need upgrade grading, with only 4% belonging to group A on final grading, difficult in bilateral
*Benjamin Joseph’s study
•Containment aims at preventing or correcting femoral head extrusion
•Factors: age at onset of symptom, femoral head extrusion (>20% Reimer migration index), ROM
•B Joseph suggested containment ASAP for
•>7, contain ASAP if still in fragmentation phase
•If reduced ROM – restore motion by traction / abduction cast for 6 weeks, treat by containment once motion is restored
•<7, monitor and contain when there is presence of extrusion
•<8: Femoral osteotomy as more remodelling and less likely to have Trendelenburg gait later
•>8: Acetabular osteotomy as there will be less shortening.
Indication for containment surgery by BJ:
•>7 or <7 with extrusion
•Stage 1a 1b 2a (still in fragmentation phase)
•Extrusion present
•Normal ROM
Contraindication
•<7 without extrusion
•Stage 2b or above
•Absent extrusion in <7 years
•Restricted ROM
Healed Perthes:
Stulberg classification
•A la carte approach
•Trendelenburg: GT osteotomy
•Hinged abduction: osteochondroplasty
•Impingement, stiffness: Valgus osteotomy
•LLD
•Coxa brevia
•Coxa vara
•Coxa plana: Pelvis osteotomy
